Lady Macbeth is a leading character in William Shakespeare's tragedy Macbeth (c.1603–1607). As the wife of the play's tragic hero, Macbeth (a Scottish nobleman), Lady Macbeth goads her husband into committing regicide, after which she becomes queen of Scotland. After Macbeth becomes a murderous tyrant, she is driven to madness by guilt over their crimes, and commits suicide offstage.
Lady Macbeth is a powerful presence in the play, most notably in the first two acts. Following the murder of King Duncan, however, her role in the plot diminishes. She becomes an uninvolved spectator to Macbeth's plotting and a nervous hostess at a banquet dominated by her husband's hallucinations. Her sleepwalking scene in the fifth act is a turning point in the play, and her line "Out, damned spot!" has become a phrase familiar to many speakers of the English language. The report of her death late in the fifth act provides the inspiration for Macbeth's "Tomorrow and tomorrow and tomorrow" speech.